Structural maintenance of chromosomes (SMC) complexes are primordial DNA modulators that are essential for genome maintenance in both prokaryotic and eukaryotic cells. Prokaryotic SMCs include members ...

Cells depend on their endolysosomal system for nutrient uptake and downregulation of plasma membrane proteins. These processes rely on endosomal maturation, which requires multiple membrane fusion ...

We tend to view ourselves and the complex cells that build us as a distinct branch of the tree of life from the compact, ...