Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function. But how and why did it come to be the way it is? "We find ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

Non-canonical amino acids can expand the scope of proteins available for therapeutics and machine learning platforms can ...

Constructive Bio’s founder and Chief Scientific Officer, Professor Jason Chin, has been named the recipient of the 2026 ...

RNA aminoacylation is controlled in biology by a unique family of synthetase enzymes 2. Curiously, these enzymes implement the rules of the genetic code but are themselves synthesized by the ribosome ...

Genetic code expansion harnesses engineered translation machinery to incorporate noncanonical amino acids into proteins at designated sites, thereby reprogramming the chemical language of living cells ...

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

The genetic code is central to life. With minor variations, everything uses the same sets of three DNA bases to encode the same 20 amino acids. We have discovered no major exceptions to this, leading ...