How proteins localize to specific compartments, function in coordination with other biomolecules and, ultimately, contribute to diverse cellular activities are crucial questions in cell biology.
Interferometric scattering microscopy (iSCAT) enables tracking single nano-objects in three dimensions (3D). Conventional image processing methods for 3D localization in iSCAT typically rely on ...
The function of the glycolytic enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study published in Molecular Cell. The enzyme uses different ...