Nature

A randomized controlled trial evaluating stress arousal reappraisal and worked example effects on psychophysiological responses during breaking bad news

Breaking bad news (BBN) is among the most distressing communication tasks in the medical field, wherein physicians disclose serious diagnoses to their patients. Under stress, physicians may resort to ...
Nature

Comparison of primary analysis strategies of randomized controlled trials with multiple endpoints with application to kidney transplantation

Relying on a single primary endpoint in randomized controlled trials (RCTs) is often infeasible, for example due to rare or heterogeneous events. Regulatory guidance therefore allows multiple ...
ascopubs.org

The lost evidence: A phase III, multicenter randomized controlled trial of neoadjuvant chemotherapy paclitaxel plus cisplatin versus surgery alone for stage IIA–IIIB ...

Exome analysis of over 5000 esophagogastric cancers. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.
BMJ Open

Cognitive-behavioural therapy for insomnia in adults to decrease cannabis use: study protocol for a randomised controlled trial in a community sample of adults with fre…

Introduction Cannabis use is common in the USA and is associated with adverse outcomes across many domains, including sleep ...
ascopubs.org

Master Protocol Design With Hybrid Control for Efficient Early-Phase Trial Consolidation

Timing of Adjuvant Chemotherapy After Gastrectomy in Patients With Stage II to III Gastric Cancer: A Target Trial Emulation Study Master protocols represent transformations, enabling multiple ...