Frontiers

Single-cell and Multi-omics Insights into Cardio-Cerebral Development and Disease: Genetic Regulation, Redox Signaling and S-nitrosylation

The heart and brain are among the earliest and most metabolically demanding organs in human development. Though historically studied in isolation, both ...

KAIST identifies new treatment target to overcome limits of anti-cancer vascular therapy

South Korean researchers have identified a new therapeutic target that could help overcome the limitations of anti-angiogenic ...
Frontiers

Dying on Their Own Terms: Ferroptosis, Cuproptosis, and the New Wave of Non Apoptotic Cell Death Reshaping Cancer Biology and Therapy

AbstractNon apoptotic cell death programs particularly ferroptosis and cuproptosis are transforming how we understand cancer ...

Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...