Cancer Res (2026) 86 (7_Supplement): 795. Hepatocellular carcinoma (HCC) is a heterogeneous malignancy, requiring spatially resolved multi-omic approaches to advance ...
We combine advanced technologies such as spatial transcriptomics, multiplexed imaging, and in situ sequencing to map cellular components in their native tissue context. Obtain high-resolution data ...
Introduction: Diabetes mellitus (DM) is associated with elevated inflammation and poorer outcomes after ischemic stroke. During the sub-acute phase of stroke, glial and fibrotic scars began to form ...
Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
A classifier to assess section integrity. (A) Generation of the transcript mask. The transcript density image was converted to a binary mask using a random forest classifier. (B) Generation of the ...
The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...
We have an in-house developed visualisation platform that can import multiple spatial biology ROIs/slides for spatial transcriptomics assays such as 10x Visium and Xenium. The current spatialdata ...
Neoadjuvant immunotherapy in combination with chemotherapy in resectable locally advanced head and neck squamous cell carcinoma: A randomized, open label, phase II clinical trial. This is an ASCO ...
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